Marlins vs. Padres Prediction, Odds, Picks – July 21
Updated Jul. 21, 2025, 6:00 p.m. ET
Data Skrive
The Miami Marlins will go head-to-head with the San Diego Padres on Monday at loanDepot Park, starting at 6:40 p.m. ET. Expect Otto Lopez and Fernando Tatis Jr. to be key players in this matchup. The Marlins are the favorites with odds of -146, while the Padres are the underdogs at +122, hoping to create an upset. Miami is favored by 1.5 runs at +149 odds, and the total runs for the game have been set at 8.
Here’s everything you need to know about betting on the Marlins vs. Padres game, covering the run line, moneyline, and total, along with expert picks. Keep up with MLB on FOX Sports!
Marlins vs. Padres Game Information & Odds
When: Monday, July 21, 2025, at 6:40 p.m. ET
Where: loanDepot Park in Miami, Florida
How to watch on TV: FDSFL and SDPA
| Favorite Moneyline | Underdog Moneyline | Total | Run Line Favorite | Underdog Run Line Odds |
| Marlins -146 | +122 | 8 | -1.5 +149 | -179 |
Marlins vs. Padres Prediction
Score Prediction: Marlins 5, Padres 4
Total Prediction: Over 8 runs
Win Probabilities: Marlins 51%, Padres 49%
Marlins vs. Padres Betting Insights
This season, the Marlins have been favored 11 times and won five of those games, giving them a 45. okebet-5% success rate. They have yet to win in four occasions when listed as favorites at -146 or more on the moneyline this season. The sportsbooks’ odds suggest a 59.3% likelihood for a victory by the Marlins.
The Padres have recorded 23 wins in 47 matches when listed as underdogs this season. They have also emerged victorious 12 times in 26 attempts when given odds of at least +122 on the moneyline, implying a 45% chance of winning according to the bookmakers.
Marlins Recent Betting Performance
The Marlins have not been the moneyline favorite in their last 10 games. In these outings, they and their opponents combined to hit the over on the run total four times, with all 10 contests having set totals. Their record against the spread is 6-4 over the last ten games.
Marlins Recent Stats
| Stat | Avg/Total |
| Record | 6-4 |
| Runs Per Game | 5.3 |
| Home Runs | 11 |
| ERA | 3.27 |
| K/9 | 7.6 |
Marlins Player Insights
Kyle Stowers leads the Marlins with 21 home runs and 59 RBIs, boasting an impressive batting average of .295. He currently ranks 14th in home runs and 22nd in RBIs among all MLB players. Otto Lopez has recorded 11 doubles, 11 home runs, and 31 walks with a batting average of .250, putting him at 108th in home runs and 52nd in RBIs this year. He has had a hit in four consecutive games.
Xavier Edwards has contributed 15 doubles, two triples, one home run, and 33 walks while hitting .286, entering this game with a five-game hitting streak. Agustin Ramirez has 21 doubles, one triple, 14 home runs, and 19 walks with a batting average of .244 ph taya login.
Marlins Team Props
| Hits O/U | Total Bases O/U | HR O/U | RBI O/U |
| Xavier Edwards 0.5 (-265) | 1.5 (+130) | – | 0. win game5 (+275) |
| Kyle Stowers 0.5 (-235) | 1.5 (+110) | – | 0.5 (+150) |
| Jesus Sanchez 0.5 (-265) | 1.5 (+105) | – | 0.5 (+165) |
| Agustin Ramirez 0.5 (-235) | 1.5 (+110) | – | 0.5 (+145) |
| Otto Lopez 1.5 (+205) | 1.5 (+115) | – | 0.5 (+170) |
Padres Recent Betting Performance
In their last ten games, the Padres have posted a 3-1 record as underdogs ah88 casino login register. They have gone over the total runs five times in these matchups, recording a 6-4-0 record against the spread in their last ten games.
Padres Recent Stats
| Stat | Avg/Total |
| Record | 6-4 |
| Runs Per Game | 3.7 |
| Home Runs | 11 |
| ERA | 3.13 |
| K/9 | 8.6 |
Padres Player Insights
Manny Machado leads the Padres with 18 home runs and 60 RBIs, while maintaining a .288 batting average. He ranks 28th in home runs and 20th in RBIs among MLB hitters. Fernando Tatis Jr. is hitting .264 with 13 doubles, two triples, and 16 home runs, along with 54 walks, ranking him 46th in home runs and 88th in RBIs. Luis Arraez and Xander Bogaerts also contribute significantly to their lineup.
Padres Team Props
| Hits O/U | Total Bases O/U | HR O/U | RBI O/U |
| Xander Bogaerts 0.5 (-205) | 1.5 (+140) | – | 0.5 (+220) |
| Manny Machado 0.5 (-235) | 1.5 (+110) | – | 0.5 (+140) |
| Jackson Merrill 0.5 (-200) | 1.5 (+145) | – | 0. phdream vip register5 (+200) |
| Gavin Sheets 0.5 (-200) | 1.5 (+125) | – | 0.5 (+160) |
| Fernando Tatis Jr. 0.5 (-235) | 1.5 (+100) | – | 0.5 (+175) |
What are your thoughts on the upcoming face-off between the Marlins and Padres?